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Guangzhou IGE Biotechnology Co., Ltd.
bet356体育在线
Guangzhou IGE Biotechnology Co., Ltd.
bet356体育在线
Guangzhou IGE Biotechnology Co., Ltd.
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[1] A small-molecule Skp1 inhibitor elicits cell death by p53-dependent mechanism.
揭晓于:iScience. 2022. PMCID: PMC9249674 IF=6.107
[2]Integrative Multi-omics Landscape of Non-structural Protein 3 of Severe Acute Respiratory Syndrome Coronaviruses.
揭晓于:Genomics Proteomics Bioinformatics. 2021. PMCID: PMC8578027 IF=6.409
引用效劳/产品：基因合成、小RNA测序
[3]Long non-coding RNA PXN-AS1 suppresses pancreatic cancer progression by acting as a competing endogenous RNA of miR-3064 to upregulate PIP4K2B expression.
揭晓于:J Exp Clin Cancer Res. 2020 PMCID: PMC7203840 IF=13.801
[4]SAA1/TLR2 axis directs chemotactic migration of hepatic stellate cells responding to injury
揭晓于:iScience. 2021 PMCID: PMC8169952 IF=6.107
引用效劳/产品：克隆构建
[5]BRD4 inhibitor GNE987 exerts anti-cancer effects by targeting super-enhancers in neuroblastoma.
揭晓于:Cell Biosci. 2022 PMCID: PMC8932231 IF=9.584
引用效劳/产品：慢病毒包装、克隆构建
[6]circ-NOL10 regulated by MTDH/CASC3 inhibits breast cancer progression and metastasis via multiple miRNAs and PDCD4.
揭晓于:Mol Ther Nucleic Acids. 2021 PMCID: PMC8526500 IF=10.183
[7]A pan-cancer analysis of CpG Island gene regulation reveals extensive plasticity within Polycomb target genes.
揭晓于:Nat Commun. 2021 PMCID: PMC8087678 IF=17.694
引用效劳/产品：siRNA合成
[8]Impairment of APPL1/Myoferlin facilitates adipogenic differentiation of mesenchymal stem cells by blocking autophagy flux in osteoporosis.
揭晓于:Cell Mol Life Sci. 2022 PMCID: PMC9391247 IF=9.207
引用效劳/产品：克隆构建
[9]Transcription factor EB-mediated mesenchymal stem cell therapy induces autophagy and alleviates spinocerebellar ataxia type 3 defects in neuronal cells model.
揭晓于:Cell Death Dis. 2022 PMCID: PMC9293975 IF=9.685
引用效劳/产品：慢病毒包装、克隆构建
[10]Circular RNA circPICALM sponges miR-1265 to inhibit bladder cancer metastasis and influence FAK phosphorylation.
揭晓于:EBioMedicine. 2019 PMCID: PMC6838432 IF=11.205
引用效劳/产品：环状RNA载体构建
[11]CLP36 promotes p53 deficient sarcoma progression through suppression of atrophin-1 interacting protein-4 (AIP-4)-dependent degradation of YAP1.
揭晓于:Theranostics. 2022 PMCID: PMC9274740 IF=11.6
引用效劳/产品：siRNA合成
[12]Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma.
揭晓于:Cell Death Dis. 2022 PMCID: PMC9132929 IF=9.685
引用效劳/产品：细胞株判断
[13]AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns.
揭晓于:Nucleic Acids Res. 2022 PMCID: PMC9122597 IF=19.16
引用效劳/产品：通俗引物合成、Qubit dsDNA HS Assay mix Kits
[14]Generation of individualized immunocompatible endothelial cells from HLA-I-matched human pluripotent stem cells.
揭晓于:Stem Cell Res Ther. 2022 PMCID: PMC8812039 IF=8.079
引用效劳/产品：细胞株判断
[15]INPP5F translocates into cytoplasm and interacts with ASPH to promote tumor growth in hepatocellular carcinoma.
揭晓于:J Exp Clin Cancer Res. 2022 PMCID: PMC8740451 IF=13.801
引用效劳/产品：克隆构建
[16]P300/CBP‐associated factor (PCAF)‐mediated acetylation of Fascin at lysine 471 inhibits its actin‐bundling activity and tumor metastasis in esophageal cancer.
揭晓于:Cancer Commun (Lond). 2021 PMCID: PMC8696220 IF=15.283
引用效劳/产品：细胞株判断
[17]MicroRNA-361-Mediated Inhibition of HSP90 Expression and EMT in Cervical Cancer Is Counteracted by Oncogenic lncRNA NEAT1.
揭晓于:Cells. 2020 PMCID: PMC7140536 IF=7.666
[18]D609 protects retinal pigmented epithelium as a potential therapy for age-related macular degeneration.
揭晓于:Signal Transduct Target Ther. 2020 PMCID: PMC7054264 IF=38.104
[19]A sensitive, accurate, and high-throughput gluco-oligosaccharide oxidase-based HRP colorimetric method for assaying lytic polysaccharide monooxygenase activity
揭晓于:Biotechnol Biofuels Bioprod. 2022 PMCID: PMC8830019 IF=7.67
[20]Osteogenic differentiation of mesenchymal stem cells promotes c-Jun-dependent secretion of interleukin 8 and mediates the migration and differentiation of CD4+ T cells.
揭晓于:Stem Cell Res Ther. 2022 PMCID: PMC8818240 IF=8.079
引用效劳/产品：siRNA合成
[21]Long noncoding RNA DIO3OS interacts with miR-122 to promote proliferation and invasion of pancreatic cancer cells through upregulating ALDOA.
揭晓于:Cancer Cell Int. 2019 PMCID: PMC6668142 IF=6.429
[22]The EGFR‐P38 MAPK axis up‐regulates PD‐L1 through miR‐675‐5p and down‐regulates HLA‐ABC via hexokinase‐2 in hepatocellular carcinoma cells.
揭晓于:Cancer Commun (Lond). 2021 PMCID: PMC7819566 IF=15.283
[23]Anti-allergic drug azelastine suppresses colon tumorigenesis by directly targeting ARF1 to inhibit IQGAP1-ERK-Drp1-mediated mitochondrial fission.
揭晓于:Theranostics. 2021 PMCID: PMC7778598 IF=11.6
[24]LncRNA KCNQ1OT1 regulates proliferation and cisplatin resistance in tongue cancer via miR-211-5p mediated Ezrin/Fak/Src signaling.
揭晓于:Cell Death Dis. 2018 PMCID: PMC7778598 IF=7.109
[25]DNA-mediated dimerization on a compact sequence signature controls enhancer engagement and regulation by FOXA1.
揭晓于:Nucleic Acids Res. 2018 PMCID: PMC6009666 IF=19.16
[26]Hemi-methylated CpG sites connect Dnmt1-knockdown-induced and Tet1-induced DNA demethylation during somatic cell reprogramming.
揭晓于:Cell Discov. 2019 PMCID: PMC6370818 IF=38.079
引用效劳/产品：通俗引物合成
[27]A humanized TCR retaining authentic specificity and affinity conferred potent anti‐tumour cytotoxicity.
揭晓于:Immunology. 2018 PMCID: PMC6099166 IF=7.215
引用效劳/产品：Sanger测序
[28]HSF1 facilitates the multistep process of lymphatic metastasis in bladder cancer via a novel PRMT5-WDR5-dependent transcriptional program.
揭晓于:Cancer Commun (Lond). 2022 PMCID: PMC9118058 IF=15.283
[29]LncRNA LINC01537 Promotes Gastric Cancer Metastasis and Tumorigenesis by Stabilizing RIPK4 to Activate NF-κB Signaling.
揭晓于:Cancers (Basel). 2022 PMCID: PMC9657364 IF=6.575
[30]The Novel Protein ADAMTS16 Promotes Gastric Carcinogenesis by Targeting IFI27 through the NF-κb Signaling Pathway.
揭晓于:Int J Mol Sci. 2022 PMCID: PMC9570124 IF=6.208
[31]PSMD2 contributes to the progression of esophageal squamous cell carcinoma by repressing autophagy.
揭晓于:Cell Biosci. 2023 PMCID: PMC10061715 IF=9.584
[32]Anchoring super-enhancer-driven oncogenic lncRNAs for anti-tumor therapy in hepatocellular carcinoma.
揭晓于:Mol Ther. 2022 PMID: 36461633 IF=12.91
[33]Circular RNA circARHGEF28 inhibited the progression of prostate cancer via the miR-671-5p/LGALS3BP/NF-κB axis.
揭晓于:Cancer Sci. 2023 PMID: 37186007 IF=6.518
[34]HHMMR promotes prostate cancer proliferation and metastasis via AURKAmTORC2E2F1 positive feedback loop.
揭晓于:Cell Death Discov. 2023 PMCID: PMC9905489 IF=7.109
[35]HPV Enhances HNSCC Chemosensitization by Inhibiting SERPINB3 Expression to Disrupt the Fanconi Anemia Pathway.
揭晓于:Adv Sci (Weinh). 2022 PMCID: PMC9811475 IF=17.521
[36]PINK1-Mediated Mitophagy Promotes Oxidative Phosphorylation and Redox Homeostasis to Induce Drug-Tolerant Persister Cancer Cells.
揭晓于:Cancer Res. 2023 PMID: 36480196 IF=13.312
[37]Profle of chimeric RNAs and TMPRSS2?ERG e2e4 isoform in neuroendocrine prostate cancer.
揭晓于:Cell Biosci. 2022 PMCID: PMC9463804 IF=9.58
[38]RNA-binding protein MEX3A controls G1S transition via regulating the RBE2F pathway in clear cell renal cell carcinoma.
揭晓于:Mol Ther Nucleic Acids. 2021 PMCID: PMC8703191 IF=10.183
[39]SYTL2 promotes metastasis of prostate cancer cells by enhancing FSCN1-mediated pseudopodia formation and invasion.
揭晓于:J Transl Med. 2023 PMCID: PMC10161564 IF=8.44
引用效劳/产品：通俗引物合成
[40]ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems.
揭晓于:BMC Biol. 2020 PMCID: PMC7510086 IF=7.364
引用效劳/产品：CRISPR sgRNA 文库效劳
[41]CRISPR/Cas9-Mediated Gene Correction in Newborn Rabbits with Hereditary Tyrosinemia Type I.
揭晓于:Mol Ther. 2021 PMCID: PMC7934638 IF=12.91
引用效劳/产品：CRISPR sgRNA 文库效劳
[42]Identification of Peptoniphilus vaginalis-Like Bacteria,Peptoniphilus septimus sp.nov., From Blood Cultures in a Cervical Cancer Patient Receiving Chemotherapy: Case and Implications.
揭晓于:Front Cell Infect Microbiol. 2022 PMCID: PMC9307962 IF=6.073
引用效劳/产品：动植物基因组de novo 测序
[43]Intranasal Administration of miR-146a Agomir Rescued the Pathological Process and Cognitive Impairment in an AD Mouse Model.
揭晓于:Mol Ther Nucleic Acids. 2019 PMCID: PMC6849368 IF=10.183
引用效劳/产品：RNA合成
[44]Loss of the RNA trimethylguanosine cap is compatible with nuclear accumulation of spliceosomal snRNAs but not pre-mRNA splicing or snRNA processing during animal development.
揭晓于:LoS Genet. 2020 PMCID: PMC7605716 IF=6.02
引用效劳/产品：小RNA 测序
[45]Efficient RNA drug delivery using red blood cell extracellular vesicles.
揭晓于:Nat Commun. 2018 PMCID: PMC6004015 IF=17.694
引用效劳/产品：细胞株判断
[46]Precise A?T to G?C base editing in the zebrafish genome.
揭晓于:BMC Biol. 2018 PMCID: PMC6247682 IF=7.364
[47]Genome-wide profiling of adenine base editor specificity by EndoV-seq.
揭晓于:Nat Commun. 2019 PMCID: PMC6325126 IF=17.694
[48]Circular RNA ACVR2A suppresses bladder cancer cells proliferation and metastasis through miR-626/EYA4 axis.
揭晓于:Molecular Cancer. 2019 PMCID: PMC652424 IF=44.144
[49]circRIP2 accelerates bladder cancer progression via miR-1305/Tgf-β2/smad3 pathway.
揭晓于:Molecular Cancer. 2020 PMCID: PMC6998850 IF=44.144
引用效劳/产品：克隆构建、基因合成、环状RNA载体构建、细胞株判断
[50]A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington’s Disease.
揭晓于:Cell. 2018 PMCID: PMC5935586 IF=66.85
引用效劳/产品：Sanger测序、通俗引物合成
[51]A CRISPR–Cas9-triggered strand displacement amplifification method for ultrasensitive DNA detection.
揭晓于:Nat Commun. 2018 PMCID: PMC6258682 IF=17.694
引用效劳/产品：通俗引物合成
[52]Quinoline Derivatives Kill Mycobacterium tuberculosis by Activating Glutamate Kinase.
揭晓于:Cell Chem Biol. 2019 PMID: 31204286 IF=9.039
[53]A standard for near-scarless plasmid construction using reusable DNA parts.
揭晓于:Nat Commun. 2019 PMCID: PMC6650416 IF=17.694
引用效劳/产品：通俗引物合成
[54]Dual-CRISPR/Cas12a-Assisted RT-RAA for Ultrasensitive SARS-CoV?2 Detection on Automated Centrifugal Microfluidics.
揭晓于:Anal Chem2022 PMID: 35775831 IF=8.008
引用效劳/产品：通俗引物合成
[55]Fn-Dps, a novel virulence factor of Fusobacterium nucleatum, disrupts erythrocytes and promotes metastasis in colorectal cancer.
揭晓于:PLoS Pathog. 2023 PMCID: PMC9873182 IF=7.464
引用效劳/产品：小RNA 测序
[56]Urolithin A protects against acetaminophen-induced liver injury in mice via sustained activation of Nrf2.
揭晓于:Int J Biol Sci. 2022 PMCID: PMC8935220 IF=10.75
引用效劳/产品：小RNA 测序
[57]CD98hc has a pivotal role in maintaining the immuno-barrier integrity of basal layer cells in esophageal epithelium.
揭晓于:Cancer Cell Int. 2022 PMCID: PMC8864845 IF=6.429
引用效劳/产品：细胞株判断
[58]Two cGAS-like receptors induce antiviral immunity in Drosophila.
揭晓于:Nature. 2021 PMID: 34261128 IF=69.504
引用效劳/产品：通俗引物合成
[59]Bioengineered bacterial outer membrane vesicles encapsulated Polybia–mastoparan I fusion peptide as a promising nanoplatform for bladder cancer immunemodulatory chemotherapy.
揭晓于:Front Immunol. 2023 PMCID: PMC10043419 IF=8.786
引用效劳/产品：Sanger测序
[60]Isolation and identifification of a salt-tolerant aerobic denitrifying bacterial strain and its application to saline wastewater treatment in constructed wetlands.
揭晓于:Bioresour Technol. 2019 PMID: 31301568 IF=11.889
引用效劳/产品：菌种判断
[61]Effificient and Safe Editing of Porcine Endogenous Retrovirus Genomes by Multiple-Site Base-Editing Editor.
揭晓于:Cells. 2022 PMCID: PMC9776866 IF=7.666
引用效劳/产品：Sanger测序
[62]The Atypical MAP Kinase MAPK15 Is Required for Lung Adenocarcinoma Metastasis via Its Interaction with NF-κB p50 Subunit and Transcriptional Regulation of Prostaglandin E2 Receptor EP3 Subtype.
揭晓于:Cancers (Basel). 2023 PMCID: PMC10000388 IF=6.575
引用效劳/产品：通俗引物合成、RNA合成、克隆构建、基因合成
[63]A Meloidogyne graminicola PectateLyase ls Involved in Virulence andActivation of Host DefenseResponses.
揭晓于:Front Plant Sci. 2021 PMCID: PMC8044864 IF=6.627
引用效劳/产品：通俗引物合成
[64]Eliminating predictable DNA off-targeteffects of cytosine base editor by using duaguiders including sgRNA and TALE.
揭晓于:Mol Ther. 2022 PMCID: PMC9263286 IF=12.91
[65]Microfluidic synthesis of manganese-alginate nanogels with self-supplyingHO2 capability for synergistic chemo/chemodynamic therapy andboosting anticancer immunity.
揭晓于:Chemical Engineering Journal.https://doi.org/10.1016/j.cej.2022.134926 IF=16.744
引用效劳/产品：小RNA 测序
[66]HNF4A-BAP31-VDAC1 axis synchronously regulates cellproliferation and ferroptosis in gastric cancer.
揭晓于:Cell Death Dis. 2023 PMCID: PMC10256786 IF=9.685
引用效劳/产品：基因合成
[67]SERPINA3-ANKRD11-HDAC3 pathway induced aromatase inhibitor resistance in breast cancer can be reversed by HDAC3 inhibition.
揭晓于:Commun Biol. 2023 PMCID: PMC10326080 IF=6.548
[68]Inhibition of phosphoglycerate dehydrogenase induces ferroptosis and overcomes enzalutamide resistance in castration-resistant prostate cancer cells .
揭晓于:Drug Resist Updat. 2023 PMID: 37423117 IF=24.3
[69]Transmembrane nuclease NUMEN/ENDOD1 regulates DNA repair pathway choice at the nuclear periphery.
揭晓于:Nat Cell Biol. 2023 PMID: 37322289 IF=28.213
引用效劳/产品：siRNA合成
[70]Decrotonylation of AKT1 promotes AKT1 phosphorylation and activation during myogenic differentiation.
揭晓于:J Adv Res. 2023 PMCID: PMC10403674 IF=10.7
[71]Upregulated LncRNA H19 Sponges MiR-106a- 5p and Contributes to Aldosterone-Induced Vascular Calcification via Activating the Runx2- Dependent Pathway.
揭晓于:Arterioscler Thromb Vasc Biol. 2023 PMID: 37409531 IF=10.514
引用效劳/产品：克隆构建、基因合成、siRNA 转染试剂
[72]UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer.
揭晓于:Cell Death Dis. 2023 PMCID: PMC10329682 IF=9.685
[73]Establishing an hTERT-driven immortalized umbilical cord-derived mesenchymal stem cell line and its therapeutic application in mice with liver failure.
揭晓于:J Tissue Eng. 2023 PMCID: PMC10510347 IF=8.2
引用效劳/产品：血卡、千血斑基因组DNA提取试剂
[74]FTO-targeted siRNA delivery by MSC-derived exosomes synergistically alleviates dopaminergic neuronal death in Parkinson’s disease via m6A-dependent regulation of ATM mRNA.
揭晓于:J Transl Med. 2023 PMCID: PMC10515429 IF=7.4
引用效劳/产品：siRNA合成
[75]Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis.
揭晓于:J Transl Med. 2023 PMCID: PMC10536727 IF=7.4
[76]Methionine orchestrates the metabolism vulnerability in cisplatin resistant bladder cancer microenvironment.
揭晓于:Cell Death Dis. 2023 PMCID: PMC10427658 IF=9.685
[77]The APCC E3 ligase subunit ANAPC11 mediates FOXO3 protein degradation to promote cell proliferation and lymph node metastasis in urothelial bladder cancer.
揭晓于:Cell Death Dis. 2023 PMCID: PMC10423259 IF=9.685
[78]Thioredoxin-interacting protein-activated intracellular potassium deprivation mediates the anti-tumour effect of a novel histone acetylation inhibitor HL23, a fangchinoline derivative, in human hepatocellular carcinoma.
揭晓于:Adv Res. 2023 PMCID: PMC10491973 IF=10.7
引用效劳/产品：克隆构建、基因合成、shRNA 设计及构建
[79]Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemia
揭晓于:Elife. 2023 Dec 11 PMCID: PMC10712958 IF=8.7
引用效劳/产品：细胞株判断
[80]Activation of STING signaling aggravates chronic alcohol exposure-induced cognitive impairment by increasing neuroinflammation and mitochondrial apoptosis
揭晓于:CNS Neurosci Ther. 2024 Mar PMCID: PMC10958405 IF=7.035
引用效劳/产品：siRNA合成
[81]CLPs-miR-103a-2-5p inhibits proliferation and promotes cell apoptosis in AML cells by targeting LILRB3 and Nrf2HO-1 axis, regulating CD8+T cell response
揭晓于:J Transl Med. 2024 Mar 14 PMCID: PMC10938737 IF=8.44
引用效劳/产品：miRNA合成
[82]Combined therapy of CAR-IL-15IL-15Rα-T cells and GLIPR1 knockdown in cancer cells enhanced anti-tumor efect against gastric cancer
揭晓于:J Transl Med. 2024 Feb 18 PMCID: PMC10874561 IF=8.44
引用效劳/产品：转录组测序
[83]Glutamine suppresses senescence and promotes autophagy through glycolysis inhibition-mediated AMPKα lactylation in intervertebral disc degeneration
揭晓于:Commun Biol. 2024 Mar 14 PMCID: PMC10940657 IF=6.548
引用效劳/产品：siRNA合成
[84]Hematopoietic Transcription Factor RUNX1 is Essential for Promoting Macrophage–Myofibroblast Transition in Non-Small-Cell Lung Carcinoma
揭晓于:Adv Sci (Weinh). 2024 Jan PMCID: PMC10767400 IF=17.521
[85]Heterologously Expressed Cellobiose Dehydrogenase Acts as Efficient Electron-Donor of Lytic Polysaccharide Monooxygenase for Cellulose Degradation in Trichoderma reesei
揭晓于:Int J Mol Sci. 2023 Dec 6 PMCID: PMC10743782 IF=6.208
[86]Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemia
揭晓于:iScience. 2023 Dec 8 PMCID: PMC10776932 IF=6.107
[87]SLC25A22 as a Key Mitochondrial Transporter Against Ferroptosis by Producing Glutathione and Monounsaturated Fatty Acids
揭晓于:Antioxid Redox Signal . 2023 Jul PMCID: PMC10620438 IF=7.468
引用效劳/产品：siRNA合成
[88]Upregulated TIMP1 facilitates and coordinates myometrial contraction by decreasing collagens and cell adhesive capacity during human labor
揭晓于:Mol Hum Reprod . 2023 Sep 30 PMCID: PMC10581194 IF=4.518
引用效劳/产品：siRNA合成
[89]VPS35 promotes gastric cancer progression through integrinFAKSRC signalling-mediated IL-6STAT3 pathway activation in a YAP-dependent manner
揭晓于:Oncogene. 2024 Jan PMCID: PMC10774127 IF=8.756
引用效劳/产品：克隆构建
[90]A Biomimetic Multifunctional Nanoframework for Symptom Relief and Restorative Treatment of Acute Liver Failure
揭晓于:ACS Nano. 2024 Jan 31 PMCID: PMC10883031 IF=17.1
引用效劳/产品：转录组测序
[91]A natural small molecule aspidosperma-type alkaloid, hecubine, as a new TREM2 activator for alleviating lipopolysaccharide-induced neuroinflammation in vitro and in vivo
揭晓于:Redox Biol. 2024 Apr PMCID: PMC10863309 IF=11.4
引用效劳/产品：克隆构建
[92]Loss of TDP?43 mediates severe neurotoxicity by suppressing PJA1 gene transcription in the monkey brain
揭晓于:Cell Mol Life Sci .2024 Jan PMCID: PMC11072099 IF=8
引用效劳/产品：克隆构建
[93]TRlM37 is a primate-specific E3 ligase for Huntingtinand accounts for the striatal degeneration inHuntington's disease
揭晓于:Sci Adv.2024 May 17 PMCID: PMC11100560 IF=13.6
引用效劳/产品：shRNA 设计及构建
[94]Tumors cells with mismatch repair deficiency induce hyperactivation of pyroptosis resistant to cell membrane damage but are more sensitive to co-treatment of IFN-γ andTNF-α to PANoptosis
揭晓于:Cell Death Discov. 2024 May 13 PMCID: PMC11091123 IF=7
引用效劳/产品：克隆构建、慢病毒包装
[95]Combined therapy of CAR-IL-15IL-15Rα-T cells and GLIPR1 knockdown in cancer cells enhanced anti-tumor efect against gastric cancer
揭晓于:J Transl Med. 2024 Feb 18 PMCID: PMC10874561 IF=7.4
引用效劳/产品：转录组测序
[96]Ailanthone ameliorates pulmonary fibrosis by suppressing JUN-dependent MEOX1 activation
揭晓于:Acta Pharm Sin B. 2024 Feb 18 IF=14.5
引用效劳/产品：克隆构建、基因合成
[97]Targeting proteasomal deubiquitinases USP14 and UCHL5with b-APl5 reduces 5-fuorouracil resistance in colorecta]cancer cells
揭晓于:Acta Pharmacol Sin. 2023 Dec PMCID: PMC1069221 IF=8.2
引用效劳/产品：克隆构建、基因合成
[98]Activation of Bivalent Gene POU4F1 Promotes and Maintains Basal-like Breast Cancer
揭晓于:Adv Sci (Weinh). 2024 May PMCID: PMC11132042 IF=15.1
引用效劳/产品：克隆构建、基因合成
[99]Dioscorea Zingiberensis New SaponinInhibits the Growth of HepatocellularCarcinoma by Suppressing theExpression of Long Non-coding RNATCONS-00026762
揭晓于:Front Pharmacol. 2021 May 3 PMCID: PMC8126712 IF=5.6
引用效劳/产品：慢病毒包装
[100]Thrombospondin-1 Regulates Trophoblast Necroptosis viaNEDD4-Mediated Ubiquitination ofTAK1 in Preeclampsia
揭晓于:Adv Sci (Weinh). 2024 Jun PMCID: PMC11151050 IF=15.1
引用效劳/产品：siRNA合成
[101]Transcription factor EHF interacting with coactivator AJUBA aggravates malignancy and acts as a therapeutic target for gastroesophageal adenocarcinoma
揭晓于:Acta Pharm Sin B. 2024 May PMCID: PMC11120281 IF=14.5
引用效劳/产品：基因合成
[102] MYL9 promotes squamous cervical cancer migration and invasion by enhancing aerobic glycolysis
揭晓于:J Int Med Res. 2023 Nov PMCID: PMC10640809 IF=1.4
引用效劳/产品：通俗引物合成
[103]Silencing circSERPINE2 restrains mesenchymal stem cell senescence via the YBX3/PCNA/p21 axis
揭晓于:Cell Mol Life Sci. 2023 Oct 1 PMCID: PMC10575817 IF=6.2
[104]IGF2BP3?mediated enhanced stability of MYLK represses MSC adipogenesis and alleviates obesity
揭晓于:Cell Mol Life Sci. 2024 Jan PMCID: PMC10776757 IF=6.2
[105]Mutant TP53 promotes invasion of lung cancer cells by regulating desmoglein 3
揭晓于:J Cancer Res Clin Oncol. 2024 Jun 20 PMCID: PMC11189974 IF=2.7
[106]The temporal association of CapZ with early endosomes regulates endosomal trafcking and viral entry into host cells
揭晓于:BMC Biol . 2024 Jan 25 PMCID: PMC10809671 IF=4.4
引用效劳/产品：克隆构建
[107]Exonuclease editor promotes precision of gene editing in mammalian cells
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引用效劳/产品：基因合成
[108]Targeting MYH9 represses USP14- mediated NAP1L1 deubiquitination and cell proliferation in glioma
揭晓于:Cancer Cell Int . 2023 Sep 28 PMCID: PMC10540345 IF=5.3
引用效劳/产品：siRNA合成
[109]Super enhancer related gene ANP32B promotes the proliferation of acute myeloid leukemia by enhancing MYC through histone acetylation
揭晓于:Cancer Cell Int . 2024 Feb 22 PMCID: PMC10882810 IF=5.3
引用效劳/产品：shRNA设计及构建、慢病毒包装
[110]Targeting macrophage M1 polarization suppression through PCAF inhibition alleviates autoimmune arthritis via synergistic NF-κB and H3K9Ac blockade
揭晓于:J Nanobiotechnology. 2023 Aug 19 PMCID: PMC10439630 10.6
引用效劳/产品：克隆构建
[111]Immunization with a multi-antigen targeted DNA vaccine eliminates chemoresistant pancreatic cancer by disrupting tumor-stromal cell crosstalk
揭晓于:J Transl Med . 2023 Oct 9 PMCID: PMC10561406 IF=6.1
[112]Integrating cfDNA liquid biopsy and organoid-based drug screening reveals PI3K signaling as a promising therapeutic target in colorectal cancer
揭晓于:J Transl Med. 2024 Feb 3 PMCID: PMC10837874 IF=6.1
引用效劳/产品：转录组测序
[113]Cirsiliol induces autophagy and mitochondrial apoptosis through the AKT/FOXO1 axis and influences methotrexate resistance in osteosarcoma
揭晓于:J Transl Med . 2023 Dec 12 PMCID: PMC10714637 IF=6.1
引用效劳/产品：siRNA合成
[114]ZSWIM4 inhibition improves chemosensitivity in epithelial ovarian cancer cells by suppressing intracellular glycine biosynthesis
揭晓于:J Transl Med . 2024 Feb 21 PMCID: PMC10880229 IF=6.1
[115]CLPs-miR-103a-2-5p inhibits proliferation and promotes cell apoptosis in AML cells by targeting LILRB3 and Nrf2/HO-1 axis, regulating CD8+T cell response
揭晓于:J Transl Med. 2024 Mar 14 PMCID: PMC10938737 IF=6.1
引用效劳/产品：克隆构建
[116]Lysine acetyltransferase 14 mediates TGF-β- induced fibrosis in ovarian endometrioma via co-operation with serum response factor
揭晓于:J Transl Med . 2024 Jun 12 PMCID: PMC11167823 IF=6.1
[117]Hypochlorous acid derived from microglial myeloperoxidase could mediate high-mobility group box 1 release from neurons to amplify brain damage in cerebral ischemia–reperfusion injury
揭晓于:J Neuroinflammation . 2024 Mar 21 PMCID: PMC10958922 IF=9.3
引用效劳/产品：shRNA设计及构建
[118]LINC01002 functions as a ceRNA to regulate FRMD8 by sponging miR-4324 for the development of COVID-19
揭晓于:Virol J. 2024 May 11 PMCID: PMC11088083 IF=4
引用效劳/产品：siRNA合成
[119]ZEB1-mediated biogenesis of circNIPBL sustains the metastasis of bladder cancer via Wnt/β-catenin pathway
揭晓于:J Exp Clin Cancer Res . 2023 Aug 2 PMCID: PMC10394821 IF=11.4
引用效劳/产品：克隆构建
[120]MKRN1 promotes colorectal cancer metastasis by activating the TGF-β signalling pathway through SNIP1 protein degradation
揭晓于:J Exp Clin Cancer Res . 2023 Aug 24 PMCID: PMC10464235 IF=11.4
引用效劳/产品：shRNA设计及构建
[121]Single-cell deconvolution algorithms analysis unveils autocrine IL11-mediated resistance to docetaxel in prostate cancer via activation of the JAK1/STAT4 pathway
揭晓于:J Exp Clin Cancer Res . 2024 Mar 1 PMCID: PMC10905933 IF=11.4
[122]ThermomiR-377-3p-induced suppression of Cirbp expression is required for effective elimination of cancer cells and cancer stem-like cells by hyperthermia
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引用效劳/产品：细胞株判断
[123]Enhancing prime editor flexibility with coiled?coil heterodimers
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引用效劳/产品：通俗引物合成
[124]Detection of Salmonella DNA and drugresistance mutation by PCR-based CRISPRlbCas12a system
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引用效劳/产品：Sanger测序
[125]The key cellular senescence related molecule RRM2 regulates prostate cancer progression and resistance to docetaxel treatment
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[126]Autophagy induces hair follicle stem cell activation and hair follicle regeneration by regulating glycolysis
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引用效劳/产品：siRNA合成
[127]A polymeric nanocarrier that eradicates breast cancer stem cells and delivers chemotherapeutic drugs
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引用效劳/产品：转录组测序
[128]Gut microbial metabolite targets HDAC3-FOXK1-interferon axis in fibroblast-like synoviocytes to ameliorate rheumatoid arthritis
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引用效劳/产品：shRNA设计及构建
[129]UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer
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引用效劳/产品：基因合成
[130]LINC01133 can induce acquired ferroptosis resistance by enhancing the FSP1 mRNA stability through forming the LINC01133-FUS-FSP1 complex
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引用效劳/产品：现货质粒
[131]Ammonium tetrathiomolybdate relieves oxidative stress in cisplatin-induced acute kidney injury via NRF2 signaling pathway
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引用效劳/产品：转录组测序
[132]SPINK1-induced tumor plasticity provides a therapeutic window for chemotherapy in hepatocellular carcinoma
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引用效劳/产品：shRNA设计及构建、克隆构建
[133]SERPINA3-ANKRD11-HDAC3 pathway induced aromatase inhibitor resistance in breast cancer can be reversed by HDAC3 inhibition
揭晓于:Commun Biol. 2023 Jul 6 PMCID: PMC10326080 IF=5.2
引用效劳/产品：修饰引物合成
[134]A Specific Mini-Intrabody Mediates Lysosome Degradation of Mutant Huntingtin
揭晓于:Adv Sci (Weinh). 2023 Nov; PMCID: PMC10625127 IF=14.3
引用效劳/产品：基因合成
[135]Potential susceptibility genes in patients with stage III and IV periodontitis: A whole-exome sequencing pilot study
揭晓于:Biomol Biomed . 2024 Jan 3 PMCID: PMC10787624 IF=3.759
[136]Activation of STING signaling aggravates chronic alcohol exposure-induced cognitive impairment by increasing neuroinflammation and mitochondrial apoptosis
揭晓于:CNS Neurosci Ther. 2024 Mar PMCID: PMC10958405 IF=4.8
引用效劳/产品：siRNA合成
[137]Single-cell RNA-seq of in vitro expanded cells from cranial neural crest reveals a rare odontogenic sub-population
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引用效劳/产品：克隆构建
[138]Phylogeography and population structure of Lagocephalus spadiceus (Richardson, 1845) (Tetraodontiformes, Tetraodontidae) in the South China Sea
揭晓于:Ecol Evol . 2024 Apr 25 PMCID: PMC11045559 IF=2.3
引用效劳/产品：Sanger测序
[139]14-3-3 protein augments the protein stability of phosphorylated spastin and promotes the recovery of spinal cord injury through its agonist intervention
揭晓于:Elife. 2024 Jan 17 PMCID: PMC10945579 IF=6.4
[140]Detection of macrolide and fluoroquinolone resistanceassociated 23S rRNA and parC mutations in Mycoplasma genitalium by nested real-time PCR
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引用效劳/产品：Sanger测序、通俗引物合成、修饰引物合成
[141]HOXA3 functions as the on-off switch to regulate the development of hESC-derived third pharyngeal pouch endoderm through EPHB2 mediated Wnt pathway
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引用效劳/产品：siRNA合成
[142]SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9
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引用效劳/产品：修饰引物合成
[143]A glucose-mediated antibiotic resistance metabolic flux from glycolysis, the pyruvate cycle, and glutamate metabolism to purine metabolism
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引用效劳/产品：PrimeScript RT reagent kit、SYBR Green Premix Pro Taq HS qPCR Kit
[144]Case report: Preimplantation genetic testing for X-linked alport syndrome caused by variation in the COL4A5 gene
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引用效劳/产品：通俗引物合成
[145]Empagliflozin alleviates atherosclerotic calcification by inhibiting osteogenic differentiation of vascular smooth muscle cells
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引用效劳/产品：转录组测序
[146]Differences in Albizia odoratissima genetic diversity between Hainan Island and mainland populations in China
揭晓于:Nat Commun. 2018 PMCID: PMC6004015 IF=17.694
引用效劳/产品：通俗引物合成
[147]Drug resistance patterns and genotype associations of Trichomonas gallinae in meat pigeons (Columba livia): insights from Guangdong Province, China
揭晓于:Front Vet Sci. 2024 Jan 9 PMCID: PMC10803545 IF=2.6
[148]A triplex crystal digital PCR for the detection of genotypes I and II African swine fever virus
揭晓于:Front Vet Sci. 2024 Apr 2 PMCID: PMC11019002 IF=2.6
引用效劳/产品：Sanger测序
揭晓于:Genes (Basel).2024 May 27 PMCID: PMC11202597 IF=2.8
引用效劳/产品：修饰引物合成
[150]Precise genome editing of the Kozak sequence enables bidirectional and quantitative modulation of protein translation to anticipated levels without affecting transcription
揭晓于:Nucleic Acids Res. 2023 Oct 13 PMCID: PMC10570039 IF=16.6
引用效劳/产品：Sanger测序、Qubit dsDNA HS Assay mix Kit
[151]Selective targeting of parallel G-quadruplex structure using L-RNA aptamer
揭晓于:Nucleic Acids Res. 2023 Nov 27 PMCID:PMC10681708 IF=16.6
引用效劳/产品：转录组测序
[152]Lnc-ZEB2-19 Inhibits the Progression and Lenvatinib Resistance of Hepatocellular Carcinoma by Attenuating the NF-κB Signaling Pathway through the TRA2A/RSPH14 Axis
揭晓于:Int 」 Biol Sci. 2023 Jul 16 PMCID: PMC10411463 IF=8.2
引用效劳/产品：shRNA 设计及构建
揭晓于:Int 」 Mol Sci. 2023 Dec 20 PMCID:PMC10778700 IF=4.9
引用效劳/产品：通俗引物合成
[154]Pioglitazone-Loaded Cartilage-Targeted Nanomicelles (Pio@C-HA-DOs) for Osteoarthritis Treatment
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引用效劳/产品：多肽合成
[155]Two cGAS-like receptors induce antiviral immunity in Drosophila
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引用效劳/产品：Sanger测序
[156]circular RNA circ-231 promotes protein biogenesis of TPI1 and PRDX6 through mediating the interaction of eIF4A3 with STAU1 to facilitate unwinding of secondary structure in 5′ UTR, enhancing progression of human esophageal squamous cell carcinoma (ESCC)
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引用效劳/产品：shRNA设计及构建、克隆构建
[157]Lymph node metastasis-related lncRNA GAS6-AS1 facilitates the progression of esophageal squamous cell carcinoma
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引用效劳/产品：shRNA设计及构建、克隆构建
[158]Super Enhancer Regulatory Gene FYB1 Promotes the Progression of T Cell Acute Lymphoblastic Leukemia by Activating IGLL1
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引用效劳/产品：shRNA设计及构建、克隆构建
[159]Gut microbiota modulate CD8+ T cell immunity in gastric cancer through Butyrate/GPR109A/HOPX
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引用效劳/产品：shRNA设计及构建、克隆构建
[160]A DNA/RNA heteroduplex oligonucleotide coupling asparagine depletion restricts FGFR2 fusion-driven intrahepatic cholangiocarcinoma
揭晓于:Mol Ther Nucleic Acids. 2023 Oct 5 PMCID: PMC10589379 IF=6.5
揭晓于:Cell Mol Gastroenterol Hepatol. 2024 Feb 28 PMCID: PMC11026735 IF=7.1
引用效劳/产品：siRNA合成
[162]Insecticide resistance reduces the profitability of insect-resistant rice cultivars
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引用效劳/产品：Sanger测序
[163]Tumor-derived apoptotic extracellular vesicle-mediated intercellular communication promotes metastasis and stemness of lung adenocarcinoma
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引用效劳/产品：shRNA设计及构建、克隆构建
[164]Conessine inhibits enveloped viruses replication through up-regulatingcholesterol level
揭晓于:Virus Res. 2023 Dec PMCID: PMC10590996 IF=2.5
引用效劳/产品：转录组测序
[165]The Expression of ZNF268 and Its Role in The Cisplatin-based Chemoresistance of Breast Cancer
揭晓于:Heliyon. 2023 Aug 19 PMCID: PMC10469720 IF=3.4
引用效劳/产品：siRNA合成
[166]GSDME has prognostic and immunotherapeutic significance in residual hepatocellular carcinoma after insufficient radiofrequency ablation
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引用效劳/产品：转录组测序
[167]Prevalence and genomic-based antimicrobial resistance analysis of Avibacterium paragallinarum isolates in Guangdong Province, China
揭晓于:Poult Sci. 2024 Jun PMCID: PMC11063509 IF=3.8
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[168]Myricanol prevents aging-related sarcopenia by rescuing mitochondrial dysfunction via targeting peroxiredoxin 5
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引用效劳/产品：基因合成
[169]The feasibility of using the compound kushen injection to treat cervical cancer based on network pharmacology and transcriptomics
揭晓于:Medicine (Baltimore).2023 Sep 8 PMCID: PMC10489532 IF=1.3
引用效劳/产品：通俗引物合成
揭晓于:Microorganisms. 2024 Feb 19 PMCID: PMC108932229 IF=4.1
引用效劳/产品：Sanger测序
[171]Mettl3?mediated m6A RNA methylation regulates osteolysis induced by titanium particles
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引用效劳/产品：shRNA设计及构建、siRNA合成
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引用效劳/产品：Sanger测序、通俗引物合成、sgRNA合成
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[174]A novel simian adenovirus-vectored COVID-19 vaccine elicits effective mucosal and systemic immunity in mice by intranasal and intramuscular vaccination regimens
揭晓于:Microbiol Spectr. 2023 Dec 12 PMCID: PMC10715068 IF=3.7
引用效劳/产品：多肽合成
[175]A protein-encoding CCDC7 circular RNA inhibits theprogression of prostate cancer by up-regulating FLRT3
揭晓于:NPj Precis Oncol. 2024 Jan 16 PMCID:PMC10789799 IF=6.8
[176]Transforming growth factor-β1protects mechanically injuredcortical murine neurons byreducing trauma-inducedautophagy and apoptosis
揭晓于:Front Cell Neurosci. 2024 May 28 PMCID: PMC11165077 IF=4.2
引用效劳/产品：修饰引物合成
[177]SNHG15-Mediated Localization of Nucleolin at the CellProtrusions Regulates CDH2 mRNA Expression andCell Invasion
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引用效劳/产品：通俗引物合成
[178]UBE2C-induced crosstalk between mono- andpolyubiquitination of SNAT2 promotes lymphaticmetastasis in bladder cancer
揭晓于:J Clin Invest. 2024 Jul 1 PMCID: PMC11213464 IF=13.3
引用效劳/产品：基因合成、克隆构建、siRNA合成、慢病毒包装
[179]Cationic lipid-polymer hybrid nanoparticle drives in situ generation andlymphatic navigation of tumor antigens to prime systemicantitumor immunity
揭晓于: nano today ，2024 Jun 8 IF=13.2
引用效劳/产品：转录组测序
[180]Exosomal miRNA-155-5p from M1-polarizedmacrophages suppresses angiogenesis bytargeting GDF6 to interrupt diabetic wound healing
揭晓于:Mol Ther Nucleic Acids. 2023 Nov 10 PMCID: PMC10701080 IF=6.5
引用效劳/产品：修饰引物合成
[181]METTL3-mediated IncRNA HOXD-ASl stability regulates inflammation,and the migration and invasion of trophoblast cells via the miR-135a/B-TRCP axis
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引用效劳/产品：克隆构建
[182]Extracellular vesicle-packaged circBlRC6from cancer-associated fbroblasts induceplatinum resistance via SUMOylationmodulation in pancreatic cancer
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引用效劳/产品：shRNA设计及构建、克隆构建
[183]Pioglitazone-Loaded Cartilage-TargetedNanomicelles (Pio@C-HA-DOs) forOsteoarthritis Treatment
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引用效劳/产品：多肽合成
[184]PITPNC1 Suppress CD8+T cell immune function and promote radioresistance in rectalcancer by modulating FASN/CD155
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引用效劳/产品：shRNA设计及构建
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揭晓于:Cell Death Discov. 2023 Nov 1 PMCID: PMC10618261 IF=8.1
引用效劳/产品：克隆构建
[186]Histone acetylation by HBO1(KAT7) activates WntB-cateninsignaling to promote leukemogenesis in B-cell acutelymphoblastic leukemia
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